BGB-11417-101 (NCT04277637) is a Phase 1a/1b, open-label, dose-escalation and expansion trial of sonrotoclax in patients with mature B-cell malignancies.
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ASPEN (NCT03053440) is a Phase 3, open-label, randomized trial comparing zanubrutinib with ibrutinib in activating MYD88 mutated (MYD88MUT) Waldenström’s macroglobulinemia (WM) patients. In an additional cohort, the efficacy and safety of zanubrutinib in MYD88 wild-type (MYD88WT) WM patients were evaluated.
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