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Area of interest
Area of interest
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Phase 1
Phase 2
Phase 3
Molecule
BG-60366
BG-68501
BG-89894
BG-C137
BG-C9074
BGB-10188
BGB-11417
BGB-16673
BGB-21447
BGB-26808
BGB-30813
BGB-43395
BGB-53038
BGB-58067
BGB-A3055
BGB-A317
BGB-A333
BGB-A445
BGB-B3227
BGB-B455
BGB-C354
BGB-DXP593
BGB-R046
Blinatumomab
Ociperlimab
Pamiparib
Sonrotoclax
Tarlatamab
Tislelizumab
Zanidatamab
Zanubrutinib
Compound type
ADC
Bi/Tri-specific
mAb
Protein degrader
Small molecule
Filters
Filter
Development phase
Phase 1
Phase 2
Phase 3
Molecule
BG-60366
BG-68501
BG-89894
BG-C137
BG-C9074
BGB-10188
BGB-11417
BGB-16673
BGB-21447
BGB-26808
BGB-30813
BGB-43395
BGB-53038
BGB-58067
BGB-A3055
BGB-A317
BGB-A333
BGB-A445
BGB-B3227
BGB-B455
BGB-C354
BGB-DXP593
BGB-R046
Blinatumomab
Ociperlimab
Pamiparib
Sonrotoclax
Tarlatamab
Tislelizumab
Zanidatamab
Zanubrutinib
Compound type
ADC
Bi/Tri-specific
mAb
Protein degrader
Small molecule
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The pipeline is updated quarterly. Last updated May 2025.
Safety and efficacy have not been established for investigational products and/or uses.
*Approved in at least one major market, such as the USA, EU, China and/or Japan.
**Phase 3 Confirmatory
References
- Amgen collaboration; BeOne has development and commercialization rights in China.
- Giffin MJ, Cooke K, Lobenhofer EK, et al. AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer. Clin Cancer Res.
2021;27:1526-1537. - Baeuerle PA, Kufer P, Bargou R. BiTE: Teaching antibodies to engage T-cells for cancer therapy. Curr Opin Mol Ther. 2009;11:22-30.
- Ahn MJ, Cho BC, Felip E, et al. Tarlatamab for Patients with Previously Treated Small-Cell Lung Cancer. N Engl J Med. 2023;389:2063-2075.
- Rojo F, Corassa M, Mavroudis D, et al. International real-world study of DLL3 expression in patients with small cell lung cancer. Lung Cancer. 2020;147:237-243.
- Zymeworks/Jazz collaboration; BeOne has exclusive development and commercialization rights in Asia (except Japan), Australia and New Zealand.
- Ensem collaboration; BeOne has global rights.
- CSPC collaboration.
- O’Bryan JP, et al. Pharmacol Res 2019;139:503-511.
- Zhu C, et al. Mol Cancer 2022;21:159.
- Izumi M, et al. J Thorac Dis 2020;12:3776-3784.
- DualityBio collaboration; BeOne has global clinical, manufacturing and commercialization rights.
- Kelly W, Danila D, Lin C, et al. Xaluritamig, a STEAP1 × CD3 XmAb 2+1 Immune Therapy for Metastatic Castration-Resistant Prostate Cancer: Results from Dose Exploration in a First-in-Human Study. Cancer Discovery. 2024;14
(1): 76–89. - Kelly W, Danila D, Lin C, et al. 1765O Interim results from a phase I study of AMG 509 (xaluritamig), a STEAP1 x CD3 XmAb 2+1 immune therapy, in patients with metastatic castration-resistant prostate cancer (mCRPC).
Annals of Oncology. 2023;34: S953-S954.